CSL Limited (ASX:CSL), parent company of CSL Behring which is based in King of Prussia, PA, recently opened the CSL Behring Biotechnology Manufacturing Facility in Melbourne, Australia. The new facility, located adjacent to the site’s manufacturing plant for plasma products, is the centerpiece of CSL’s $250 million expansion at its Broadmeadows site and will play an increasingly important role in the company’s global operations, particularly in the late-stage development of new types of hemophilia products. It is one of the largest and most advanced facilities of its kind in the world and will produce novel recombinant therapies on a large scale for international clinical trials.
The company’s recombinant factor development programs, which comprise the AFFINITY trial and the PROLONG trial for the study of therapies to treat hemophilia A and B, respectively, are central to its long-term growth plans. Several candidates in these trials are showing promise, including rVIII-SingleChain, rIX-FP, and rVIIa-FP.